تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Outcome of pregnancy in patients with inactive systemic lupus erythromatosus and minimal proteinuria
Outcome of pregnancy in patients with inactive systemic lupus erythromatosus and minimal proteinuria
 
الموضوع : أمراض الكلى 
لغة الوثيقة : الانجليزية 
المستخلص : Systemic lupus erythematosus (SLE) is a multisystem disease. This study was undertaken to assess the outcome of pregnancies in patients with inactive SLE. We prospectively studied 20 female patients with diagnosis of stable class IV Lupus nephritis followed up at King Abdul Aziz University Hospital, in Jeddah, Saudi Arabia between 1998 and 2008. Before each pregnancy all the patients had their blood pressure, serum creatinine, creatinine clearance, serology for SLE and 24-hour urine protein excretion measured and then repeated at monthly intervals during the pregnancy. Statistical analysis was performed using the Wilcoxon signed-rank test. Despite having negative antinuclear antibody (ANA) significant complications were observed during pregnancy. The daily proteinuria during 34-36 weeks' gestation was significantly higher (P< 0.05) than during 32 weeks. Two patients had abortions one stillbirth and 2 required termination of the pregnancy; one due to severe hypertension, and other due to renal impairment. One patient developed HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome. 14 patients had a successful pregnancy, including 4 requiring a cesarian section. In conclusion, although no clinical evidence of lupus disease activity was demonstrated pre-conception proteinuria significantly increased during pregnancy along with maternal and fetal complications. Pregnant females with diagnosis of SLE need a multidisciplinary care during the pregnancy and post-partum period 
ردمد : 1319-2442 
اسم الدورية : المجلة السعودية لأمراض وزرع الكلى 
المجلد : 20 
العدد : 5 
سنة النشر : 1430 هـ
2009 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Wednesday, August 3, 2011 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
سعد الشهيبAl-Shohaib, Saad باحثدكتوراه 

الملفات

اسم الملفالنوعالوصف
 30003.pdf pdf 

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